Knouse Lab

Massachusetts Institute of Technology

New review!

Our liver can completely regenerate itself in a matter of days! Excited to share Kristin’s perspective on how the liver breaks the rules of cell biology to accomplish this exceptional feat and how this could unlock regenerative capacity in other organs.

Monica wins best poster by a junior student at the MIT Biological Engineering Undergraduate Research Symposium

Congratulations Monica!

Congratulations to Monica Petulla for winning the prize for best poster by a junior student at the MIT Biological Engineering Undergraduate Research Symposium!

Tina presents her research at the St. Jude National Graduate Student Symposium

Congratulations Tina!

Congratulations to Tina Lopez for being selected to present her research at the St. Jude National Graduate Student Symposium!

New review!

Can we perform genome-wide screens in any cell type in the body?! Excited to share Tess Fallon’s roadmap for leveraging advances in sgRNA delivery, library design, and phenotypic selection to enable unprecedented genetic dissection of organismal physiology and disease.

Tina wins best poster at the Irwin M. Arias Symposium

Congratulations Tina!

Congratulations to Tina Lopez for receiving the prize for best poster at the annual Irwin M. Arias Symposium!

Celebrating Tess' NSF Graduate Fellowship and Sarit's acceptance into graduate school

Congratulations Tess and Sarit!

Congratulations to Tess Fallon for receiving the NSF Graduate Fellowship and to Sarit Radak for being accepted into graduate school! We are thrilled to have Tess launch a new area of research in the lab and look forward to following all that Sarit accomplishes in his next training stage!

Tina presents her research at the University of Utah Rising Stars Symposium

Congratulations Tina!

Congratulations to Kristina Lopez for being named a University of Utah Biochemistry Rising Star! Kristina’s fearlessness and determination have forged exciting new frontiers in our lab and we are so proud of her for receiving this well-deserved recognition!

Our lab’s first paper!

Our lab’s first paper in which we establish genome-wide CRISPR screening in the mouse liver is now published online at Cell Genomics! We are so excited about the power of this platform to enable high-throughput genetic dissection of diverse phenomena within a living mammal.

Kristin’s interview with MIT News

Kristin enjoyed talking to MIT News about how she fell in love with liver regeneration and how she hopes it can inspire new therapies for organ injury and cancer. Check out this behind-the-scenes footage of our new lab!

We have moved!

Kristin has joined the MIT Department of Biology as an Assistant Professor and our lab has relocated to the Koch Institute for Integrative Cancer Research at MIT! We are thrilled to be part of this interdisciplinary environment unified by a mission to advance our understanding and treatment of human disease.​